Permeability of the mammary gland to large antibiotic molecules.

  title={Permeability of the mammary gland to large antibiotic molecules.},
  author={G. Ziv and F. Sulman},
  journal={Zentralblatt fur Veterinarmedizin. Reihe A},
  volume={20 5},
  • G. Ziv, F. Sulman
  • Published 1973
  • Chemistry, Medicine
  • Zentralblatt fur Veterinarmedizin. Reihe A
  • Summary The permeability of the blood-milk barrier to systemically administered spiramycin (m. w. 920), polymyxin B (m. w. 1,220), vancomycin (m. w. 3,200) and ristocetin (m. w. 5,000) was examined in lactating cows and ewes. Spiramycin penetrated into milk in accordance with the pH-pK non-ionic diffusion principle. Limited penetration of polymyxin B and vancomycin was observed while ristocetin was not detected in milk in spite of serum drug levels in excess of 10.0 mcg./ml… CONTINUE READING
    3 Citations
    Distribution and Blood-to-Milk Transfer of Labeled Antibiotics
    • 7
    • PDF
    Pharmacokinetics of spiramycin after intravenous, intramuscular and subcutaneous administration in lactating cows.
    • 9
    Antibacterial drugs used against mastitis in cattle by the systemic route.
    • 13


    Binding of Antibiotics to Bovine and Ovine Serum
    • G. Ziv, F. Sulman
    • Biology, Medicine
    • Antimicrobial Agents and Chemotherapy
    • 1972
    • 72
    • PDF
    Placental transmission of colistimethate
    • 7
    Ristocetin, a laboratory and clinical evaluation in children.
    • 8
    Outline of details for microbiological assays of antibiotics: second revision.
    • 218
    Serum and milk concentrations of spectinomycin and tylosin in cows and ewes.
    • 24
    Polymyxin, colistin and bacitracin.
    • E. Jawetz
    • Medicine
    • Pediatric clinics of North America
    • 1961
    • 17
    Mammary excretion of benzylpenicillin, erythromycin, and penethamate hydroiodide.
    • 57