Permeability of the blood–brain barrier depends on brain temperature

  title={Permeability of the blood–brain barrier depends on brain temperature},
  author={Eugene A Kiyatkin and Hari Shanker Sharma},
Increased permeability of the blood-brain barrier (BBB) has been reported in different conditions accompanied by hyperthermia, but the role of brain temperature per se in modulating brain barrier functions has not been directly examined. To delineate the contribution of this factor, we examined albumin immunoreactivity in several brain structures (cortex, hippocampus, thalamus and hypothalamus) of pentobarbital-anesthetized rats (50 mg/kg i.p.), which were passively warmed to different levels… CONTINUE READING
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