Permeability of lipid bilayers to methylmercuric chloride: quantification by fluorescence quenching of a carbazole-labeled phospholipid.

Abstract

We investigated the permeabilities of lipid bilayers to the neurotoxin methylmercuric chloride (MMC). This mercurial is an efficient collisional quencher of the fluorescence of N-alkyl carbazole derivatives. Quenching of the fluorescence of beta-(3-(9-carbazole)-propionyl-L-alpha-phosphatidylcholine (CPA-PC) in vesicles of dimyristoyl phosphatidylcholine… (More)

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