Permeability and stability in buffer and in human serum of fluorinated phospholipid-based liposomes.

@article{Frzard1994PermeabilityAS,
  title={Permeability and stability in buffer and in human serum of fluorinated phospholipid-based liposomes.},
  author={Fr{\'e}d{\'e}ric Fr{\'e}zard and Catherine Santaella and Pierre Vierling and Jean G. Riess},
  journal={Biochimica et biophysica acta},
  year={1994},
  volume={1192 1},
  pages={61-70}
}
The stability (with respect to encapsulated carboxyfluorescein release) of fluorinated liposomes and their membrane permeability have been investigated in buffer and in human serum as compared to conventional hydrogenated analogues. These fluorinated liposomes are made from highly fluorinated phosphatidylcholines and contain a fluorinated core within their membrane. In buffer and in their fluid state, the fluorinated liposomes retain much more efficiently their entrapped content and display… CONTINUE READING