Permeability Changes of Integrin-Containing Multivesicular Structures Triggered by Picornavirus Entry


Cellular uptake of clustered α2β1-integrin induces the formation of membrane compartments that subsequently mature into a multivesicular body (MVB). Enhanced internalization mediated by clustered integrins was observed upon infection by the picornavirus echovirus 1 (EVI). We elucidated the structural features of virus-induced MVBs (vMVBs) in comparison to… (More)
DOI: 10.1371/journal.pone.0108948


6 Figures and Tables