Permeability–diffusivity modeling vs. fractional anisotropy on white matter integrity assessment and application in schizophrenia☆


INTRODUCTION Diffusion tensor imaging (DTI) assumes a single pool of anisotropically diffusing water to calculate fractional anisotropy (FA) and is commonly used to ascertain white matter (WM) deficits in schizophrenia. At higher b-values, diffusion-signal decay becomes bi-exponential, suggesting the presence of two, unrestricted and restricted, water pools… (More)
DOI: 10.1016/j.nicl.2013.06.019


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