Permeabilities of rebamipide via rat intestinal membranes and its colon specific delivery using chitosan capsule as a carrier.

@article{Huang2008PermeabilitiesOR,
  title={Permeabilities of rebamipide via rat intestinal membranes and its colon specific delivery using chitosan capsule as a carrier.},
  author={Bei-bei Huang and Guo-feng Li and Jing-Hui Luo and Lian Duan and Kishimoto Nobuaki and Yamamoto Akira},
  journal={World journal of gastroenterology},
  year={2008},
  volume={14 31},
  pages={
          4928-37
        }
}
AIM To investigate the permeability characteristics of rebamipide across intestinal mucosa, and examine the effects of some absorption enhancers on the permeability across the colonic tissue. Another purpose is to demonstrate the colon-specific delivery of rebamipide with or without absorption enhancers using chitosan capsule as a carrier. METHODS The permeability of rebamipide was evaluated using an in vitro diffusion chamber system, and the effects of some absorption enhancers on the… Expand
Biopharmaceutical characterization of rebamipide: the role of mucus binding in regional-dependent intestinal permeability.
Chitosan: a potential polymer for colon-specific drug delivery system
Development of novel bilayer gastroretentive tablet based on hydrophobic polymers.
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