Periventricular nodular heterotopia with overlying polymicrogyria.

@article{Wieck2005PeriventricularNH,
  title={Periventricular nodular heterotopia with overlying polymicrogyria.},
  author={Gretchen Wieck and Richard Jacob Leventer and Waney M Squier and An Jansen and Eva Andermann and François Dubeau and Anna Ramazzotti and Renzo Guerrini and William B Dobyns},
  journal={Brain : a journal of neurology},
  year={2005},
  volume={128 Pt 12},
  pages={2811-21}
}
Polymicrogyria (PMG) and periventricular nodular heterotopia (PNH) are two developmental brain malformations that have been described independently in multiple syndromes. Clinically, they present with epilepsy and developmental handicaps in both children and adults. Here we describe their occurrence together as the two major findings in a group of at least three cortical malformation syndromes. We identified 30 patients as having both PNH and PMG on brain imaging, reviewed clinical data and… CONTINUE READING
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