Periventricular leukomalacia with late-onset circulatory dysfunction of premature infants: correlation with severity of magnetic resonance imaging findings and neurological outcomes.

@article{Kobayashi2006PeriventricularLW,
  title={Periventricular leukomalacia with late-onset circulatory dysfunction of premature infants: correlation with severity of magnetic resonance imaging findings and neurological outcomes.},
  author={Satoru Kobayashi and Shinji Fujimoto and Sumio Fukuda and Ayako Hattori and Toshimitsu Iwaki and Norihisa Koyama and Taihei Tanaka and Minoru Kokubo and Tohru Okanishi and Hajime Togari},
  journal={The Tohoku journal of experimental medicine},
  year={2006},
  volume={210 4},
  pages={333-9}
}
The incidence of late-onset circulatory dysfunction (LCD) of premature infants, which is characterized by sudden hypotension and oliguria, has recently increased in Japan. This condition suddenly occurs after several days of age without obvious causes in preterm infants with stable respiration and circulation. Intravenous steroids frequently improve the hypotension. The main problem with LCD is the subsequent and frequent onset of periventricular leukomalacia (PVL), and neurological development… CONTINUE READING
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