Perivascular stem cells: a prospectively purified mesenchymal stem cell population for bone tissue engineering.

@article{James2012PerivascularSC,
  title={Perivascular stem cells: a prospectively purified mesenchymal stem cell population for bone tissue engineering.},
  author={Aaron Watkins James and Janette N. Zara and Xinli Zhang and Asal Askarinam and Raghav Goyal and Michael Chiang and Wei Ning Yuan and Le Chang and Mirko Corselli and Jia Cong Shen and Shen Pang and David Stoker and Ben Wu and Kang Ting and Bruno P{\'e}ault and Chia Soo},
  journal={Stem cells translational medicine},
  year={2012},
  volume={1 6},
  pages={
          510-9
        }
}
Adipose tissue is an ideal source of mesenchymal stem cells for bone tissue engineering: it is largely dispensable and readily accessible with minimal morbidity. However, the stromal vascular fraction (SVF) of adipose tissue is a heterogeneous cell population, which leads to unreliable bone formation. In the present study, we prospectively purified human perivascular stem cells (PSCs) from adipose tissue and compared their bone-forming capacity with that of traditionally derived SVF. PSCs are a… CONTINUE READING

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