Perivascular dendritic macrophages as immunobiological constituents of the human dermal microvascular unit.

We have recently observed a previously uncharacterized population of class II (Ia) antigen-positive dendritic cells that is intimately associated with the dermal microvessels of normal human adult and newborn skin. Immunofluorescence and immunoelectron microscopy studies have indicated that this cell is a perivascular macrophage. This dermal perivascular… CONTINUE READING