Perivascular adipose tissue as a messenger of the brain-vessel axis: role in vascular inflammation and dysfunction.

@article{Guzik2007PerivascularAT,
  title={Perivascular adipose tissue as a messenger of the brain-vessel axis: role in vascular inflammation and dysfunction.},
  author={Tomasz J. Guzik and Paul J. Marvar and Marta Cześnikiewicz-Guzik and Ryszard Korbut},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2007},
  volume={58 4},
  pages={591-610}
}
Perivascular adipose tissue AT is a critical regulator of vascular function, which until recently has been greatly overlooked. Virtually all arteries are surrounded by a significant amount of perivascular adipose tissue, which has long been considered to serve primarily a supportive, mechanical purpose. Recent studies show that both visceral and perivascular fat is a very active endocrine and paracrine source of inflammatory cytokines and adipokines. The latter include beneficial adipocytokines… CONTINUE READING

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