Perivascular adipose tissue and mesenteric vascular function in spontaneously hypertensive rats.

@article{Glvez2006PerivascularAT,
  title={Perivascular adipose tissue and mesenteric vascular function in spontaneously hypertensive rats.},
  author={Beatriz G G{\'a}lvez and Javier de Castro and Diana Herold and Galyna Dubrovska and Silvia M Arribas and Mar{\'i}a Del Carmen S{\'a}enz Gonz{\'a}lez and Isabel Ar{\'a}nguez and Friedrich C. Luft and Maria Pilar Ramos and Maik Gollasch and Maria S Fern{\'a}ndez Alfonso},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2006},
  volume={26 6},
  pages={1297-302}
}
OBJECTIVE Perivascular adipose tissue of normotensive rats releases a transferable factor that induces relaxation by opening voltage-dependent K+ (Kv) channels. The relevance of these observations to hypertension is unknown. METHODS AND RESULTS We characterized mesenteric perivascular adipose tissue from 3-month-old Wistar Kyoto rats (WKY) and aged-matched spontaneously hypertensive rats (SHR). Mesenteric bed (MB) weight and MB total lipid content were lower in SHR than in WKY. Freshly… CONTINUE READING
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