Peritubular capillary regression during the progression of experimental obstructive nephropathy.

@article{Ohashi2002PeritubularCR,
  title={Peritubular capillary regression during the progression of experimental obstructive nephropathy.},
  author={Ryuji Ohashi and Akira Shimizu and Yukinari Masuda and Hiroshi Kitamura and Masamichi Ishizaki and Yuichi Sugisaki and Nobuaki Yamanaka},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2002},
  volume={13 7},
  pages={1795-805}
}
Injury to the renal microvasculature may be a major factor contributing to the progression of renal disease. Although severe disruption of peritubular capillaries (PTC) could lead to marked tubulointerstitial scarring, elucidation of that process remains incomplete. This study investigated the morphologic changes in PTC and their likely regulation by vascular endothelial growth factor (VEGF) during the progression of tubulointerstitial injuries. Unilateral ureteral obstruction was induced in… CONTINUE READING

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