Peritoneal Ly-1 B cells: genetic control, autoantibody production, increased lambda light chain expression.

@article{Hayakawa1986PeritonealLB,
  title={Peritoneal Ly-1 B cells: genetic control, autoantibody production, increased lambda light chain expression.},
  author={Kyoko Hayakawa and Richard R Hardy and Leonard A. Herzenberg},
  journal={European journal of immunology},
  year={1986},
  volume={16 4},
  pages={450-6}
}
Previous studies demonstrate that Ly-1 B cells and their progenitors are clearly detectable in peritoneum in normal mice. In this publication, we show (a) that peritoneal Ly-1 B cells resemble splenic Ly-1 B cells with respect to surface marker expression and functional activity (autoantibody production); (b) that Ly-1 B frequencies in peritoneum are considerably higher than in spleen; and (c) that genetic mechanisms reduce peritoneal Ly-1 B frequencies to minimal levels in SJL-related mice and… CONTINUE READING

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