Perisynaptic barrier of proteoglycans in the mature brain and spinal cord.

@article{Murakami2003PerisynapticBO,
  title={Perisynaptic barrier of proteoglycans in the mature brain and spinal cord.},
  author={Takuro Murakami and Aiji Ohtsuka},
  journal={Archives of histology and cytology},
  year={2003},
  volume={66 3},
  pages={195-207}
}
Cell bodies and their dendrites of motor neurons, motor-related neurons, and certain other subsets of neurons such as GABAergic interneurons in the mature brain and spinal cord possess intensely negatively charged perineuronal or perisynaptic nets of proteoglycans which are linked to the nerve cell surface glycoproteins. These perineuronal nets of proteoglycans are digested by chondroitinase ABC, hyaluronidase, or collagenase, but not by endo-alpha-N-acetylgalactosaminidase, which is reactive… CONTINUE READING
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