Peripherally injected CCK-8S activates CART positive neurons of the paraventricular nucleus in rats.

@article{Peter2010PeripherallyIC,
  title={Peripherally injected CCK-8S activates CART positive neurons of the paraventricular nucleus in rats.},
  author={Lisa Peter and Andreas Stengel and Steffen Noetzel and Tobias Inhoff and Miriam Goebel and Yvette F. Tach{\'e} and R{\"u}diger W Veh and Norbert Bannert and Carsten Gr{\"o}tzinger and Bertram J Wiedenmann and Burghard F. Klapp and Hubert M{\"o}nnikes and Peter Kobelt},
  journal={Peptides},
  year={2010},
  volume={31 6},
  pages={1118-1123}
}
Cholecystokinin (CCK) plays a role in the short-term inhibition of food intake. Cocaine- and amphetamine-regulated transcript (CART) peptide has been observed in neurons of the paraventricular nucleus (PVN). It has been reported that intracerebroventricular injection of CART peptide inhibits food intake in rodents. The aim of the study was to determine whether intraperitoneally (ip) injected CCK-8S affects neuronal activity of PVN-CART neurons. Ad libitum fed male Sprague-Dawley rats received 6… CONTINUE READING

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