Peripheral-type benzodiazepine receptors.

  title={Peripheral-type benzodiazepine receptors.},
  author={A L Parola and Henry I. Yamamura and Hugh E. Laird},
  journal={Life sciences},
  volume={52 16},
Since their first description as anomalous high affinity diazepam binding sites in rat peripheral tissues, the peripheral-type benzodiazepine receptor (PBR) has been increasingly studied to better understand nonneural effects of the benzodiazepines. The mammalian PBR is ubiquitously distributed with high concentrations in the outer mitochondrial membrane of secretory tissues. In regions of the brain, the density of PBR can equal or exceed the density of central-type benzodiazepine receptors… CONTINUE READING


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