Peripheral thermosensation in mammals

  title={Peripheral thermosensation in mammals},
  author={Joris Vriens and Bernd Nilius and Thomas Voets},
  journal={Nature Reviews Neuroscience},
Our ability to perceive temperature is crucial: it enables us to swiftly react to noxiously cold or hot objects and helps us to maintain a constant body temperature. Sensory nerve endings, upon depolarization by temperature-gated ion channels, convey electrical signals from the periphery to the CNS, eliciting a sense of temperature. In the past two decades, we have witnessed important advances in our understanding of mammalian thermosensation, with the identification and animal-model assessment… CONTINUE READING


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