Peripheral pathways regulate motoneuron collateral dynamics.

  title={Peripheral pathways regulate motoneuron collateral dynamics.},
  author={Richard J. Redett and Rajesh Jari and Thomas Crawford and You-Gang Chen and Charles Rohde and Thomas M Brushart},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={25 41},
Motor axons regenerating after repair of mixed nerve reinnervate pathways leading to muscle more often than those leading to skin [preferential motor reinnervation (PMR)]. Motoneurons that initially project collaterals to both muscle and skin prune incorrect projections to generate specificity. The number of motor axon collaterals maintained entirely within cutaneous or muscle pathways, however, is unknown. To overcome this shortcoming, dorsal root ganglion excision has been used to allow only… CONTINUE READING

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