Peripheral nervous system insulin resistance in ob/ob mice

@inproceedings{Grote2013PeripheralNS,
  title={Peripheral nervous system insulin resistance in ob/ob mice},
  author={Caleb W. Grote and Anna L Groover and Janelle M. Ryals and Paige C Geiger and Eva L. Feldman and Douglas E Wright},
  booktitle={Acta neuropathologica communications},
  year={2013}
}
BACKGROUND A reduction in peripheral nervous system (PNS) insulin signaling is a proposed mechanism that may contribute to sensory neuron dysfunction and diabetic neuropathy. Neuronal insulin resistance is associated with several neurological disorders and recent evidence has indicated that dorsal root ganglion (DRG) neurons in primary culture display altered insulin signaling, yet in vivo results are lacking. Here, experiments were performed to test the hypothesis that the PNS of insulin… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Effects of insulin on peripheral nerves.

Journal of diabetes and its complications • 2016
View 3 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Phosphorylation of IRS proteins, insulin action, and insulin resistance.

American journal of physiology. Endocrinology and metabolism • 2009
View 17 Excerpts
Highly Influenced

Insulin resistance in the nervous system.

Trends in endocrinology and metabolism: TEM • 2012
View 2 Excerpts

Similar Papers

Loading similar papers…