Peripheral nerve stimulation increases serotonin and dopamine metabolites in rat spinal cord

@article{Men1994PeripheralNS,
  title={Peripheral nerve stimulation increases serotonin and dopamine metabolites in rat spinal cord},
  author={Di-Sheng Men and Yoichiro Matsui},
  journal={Brain Research Bulletin},
  year={1994},
  volume={33},
  pages={625-632}
}
Extracellular serotonin (5-HT), dopamine (DA), and their metabolites, 5-hydroxyindoleacetic acid (5-HIAA), 3,4-dihydroxyphenylacetic acid (DOPAC), and homovanillic acid (HVA), were assessed in the rat lumbar spinal cord (L3-4) by in vivo microdialysis with high performance liquid chromatography and electrochemical detection (HPLC-ECD). Under urethane-chloralose anesthesia, basal levels of 5-HT and DA in the dialysates were approximately 1.0-1.2 pg/22 microliters sample, 5-HIAA, DOPAC, and HVA… CONTINUE READING

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