Peripheral nerve function is increasingly impaired during puberty in adolescents with type 1 diabetes.

@article{Riihimaa2001PeripheralNF,
  title={Peripheral nerve function is increasingly impaired during puberty in adolescents with type 1 diabetes.},
  author={P H Riihimaa and Kalervo Suominen and Uolevi Tolonen and Virva J{\"a}ntti and Mikael Knip and P{\"a}ivi Tapanainen},
  journal={Diabetes care},
  year={2001},
  volume={24 6},
  pages={
          1087-92
        }
}
OBJECTIVE To evaluate the impact of puberty on peripheral nerve function in adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS Of 138 eligible patients with type 1 diabetes, 100 patients (age >9 years and diabetes duration >2 years) attending an outpatient diabetes clinic and 100 age- and sex-matched healthy control subjects took part in this cross-sectional study. Peripheral motor and sensory nerve conduction tests, cardiovascular reflex tests on the autonomic nervous system, and… 
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43 Citations
Background Citations
15
Results Citations
2

43 Citations

Citation Type

Citation Type

Electrophysiological Characterization of Neuropathy Complicating Type 1 Diabetes Mellitus
TLDR
The most frequent neurophysiological abnormality was the conduction slowing, and the common peroneal was the most vulnerable nerve, which signify generation of a protocol for early screening of neuropathy in children with type 1 diabetes.
[Subclinical peripheral neuropathy in type 1 diabetic adolescents and its relationship with metabolic control].
TLDR
Better metabolic control can slow the progression of subclinical peripheral neural dysfunction in type 1 diabetic paediatric patients during the second decade of life, and its relationship with metabolic control is evaluated.
Validity of the neurological examination in diagnosing diabetic peripheral neuropathy.
Neurophysiological evaluation in newly diagnosed Diabetes Mellitus type 1
TLDR
The study underline the significance of early neurophysiological diagnosis, since hyperglycemia can play an acute role in NCV slowing, despite the absence of clinical symptoms, particularly in the first three months after the diagnosis has been confirmed.
Peripheral neuropathy in children with type 1 diabetes.
Relationship of Serum Vitamin D levels with Nerve Conduction Velocity in patients of Diabetic Neuropathy
TLDR
Nerve conduction velocities and vitamin D deficiency might be independently associated with diabetic peripheral neuropathy, so these investigative parameters could be used as an independent marker to assess the severity of the neuropathy.
Peripheral and Autonomic Neuropathy Status of Young Patients With Type 1 Diabetes Mellitus at the Time of Transition From Pediatric Care to Adult-Oriented Diabetes Care
TLDR
Rydel-Seiffer tuning fork and Tiptherm®-tests revealed peripheral sensory neurological impairments in young T1DM patients at the time of their transition to adult diabetes care, and cardiovascular autonomic neuropathy and cardiac morphological alterations could not be found.
Evaluation of median nerve in children with type1 diabetes using ultrasonographic imaging and electrophysiology
Diabetic neuropathy in children and adolescents with type 1 diabetes mellitus: Diagnosis, pathogenesis, and associated genetic markers
TLDR
A number of recently identified genes, including the AKR1B1, VEGF, MTHFR, APOE, and ACE genes, contribute significantly in the pathogenesis of DN and may serve as biomarkers to predict future DN development or treatment response.
Peripheral Neuropathy in Children and Adolescents with Insulin-dependent Diabetes Mellitus
TLDR
Rigid blood glucose control and periodic neurological examinations were the best strategies to prevent Diabetic peripheral neuropathy among T1DM patients.
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References

SHOWING 1-10 OF 26 REFERENCES
Nerve conduction and autonomic nerve function in diabetic children. A 10‐year follow‐up study
In order to study the long‐term development of diabetic neuropathy in children with newly diagnosed diabetes mellitus, 144 children were entered in a prospective study of nerve conduction and…
Prospective Assessment of Autonomic and Peripheral Nerve Function in Adolescents with Diabetes
TLDR
It is suggested that more than 3 years of follow-up is required to detect evolving neuropathy in this age group of adolescents with Type 1 diabetes, as a low rate of neurological abnormalities was found.
PERIPHERAL NEUROPATHY IN DIABETIC CHILDREN AND ADOLESCENTS
TLDR
Motor conduction velocity determination of the peroneal nerve can be used both in revealing and following the abnormality in peripheral nervous function in diabetic children, and regular follow‐up of nervous function test results may help in assessing the importance of good metabolic control in preventing diabetic complications.
Prevalence of peripheral neuropathy with insulin-dependent diabetes mellitus.
Role of Height and Glycosylated Hemoglobin in Abnormal Nerve Conduction in Pediatric Patients With Type I Diabetes Mellitus After 4–9 yr of Disease
Objective To determine the role of height and glycosylated hemoglobin in abnormal nerve conduction in pediatric patients with insulin-dependent (type I) diabetes mellitus. Research Design And Methods…
Factors in Development of Diabetic Neuropathy: Baseline Analysis of Neuropathy in Feasibility Phase of Diabetes Control and Complications Trial (DCCT)
  • Medicine
    Diabetes
  • 1988
TLDR
The somatic and autonomic test results confirm the relationship between age, diabetes duration, and male gender and diabetic neuropathy, and support an effect of age and gender on the development of diabetic complications.
Autonomic neuropathy in type I diabetes: influence of duration and other diabetic complications.
TLDR
The E/I ratio and the acceleration index were especially low in patients with retinopathy as well as in patients of type I diabetic patients with symptoms of AN if combined with peripheral neuropathy (PN), and the brake index was low in Patients with Symptoms of AN independent of PN.
Evolution of nerve conduction velocity in later childhood and adolescence
TLDR
According to these results, changes occur in the function—and thus probably also in the morphology—of peripheral nerves even in later childhood and adolescence, which pertain to general maturation, growth in length of the limbs, and possibly also sex.
Epidemiological Correlates of Diabetic Neuropathy: Report From Pittsburgh Epidemiology of Diabetes Complications Study
TLDR
Traditional cardiovascular risk factors (e.g., lipids and smoking) are important determinants of distal symmetric polyneuropathy and if confirmed in prospective follow-up, open new avenues to the prevention of diabetic neuropathy.
The Vibratory Perception Threshold in Young Diabetic Patients: Associations with Glycemia and Puberty
TLDR
The data indicate that vibratory perception threshold abnormalities occur early in the course of type I diabetes mellitus; however, they are more evident in those patients who are postpubertal, and suggest that the association between the vibratory Perception threshold and glycemia may be modified by developmental factors.
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