Peripheral nerve abnormalities in the diabetic mutant mouse.

  title={Peripheral nerve abnormalities in the diabetic mutant mouse.},
  author={Ajay K Sharma and Professor P. K. Thomas and Gerardo Gabriel and Christopher Stolinski and Peter Dockery and Graham W Hollins},
  volume={32 12},
Observations were made on the genetically diabetic C57BL/Ks (db/db) mouse. Morphometric observations were performed on the tibial nerve at 6, 9, and 15 mo and compared with those from nondiabetic (m/m) controls. Myelinated fiber size was less in the diabetic animals at all stages and affected cross-sectional axon area and myelin thickness equally. Unmyelinated axons were unaffected. The index of circularity of myelinated axons did not differ between diabetic and control animals. No definite… CONTINUE READING