Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients

  title={Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients},
  author={Aiman Abrahim and Gert Luurtsema and Martin Peter Bauer and Rudolf Karch and Mark Lubberink and Ekaterina Pataraia and Christian Joukhadar and Kurt Kletter and Adriaan A. Lammertsma and Christoph Baumgartner and Markus M{\"u}ller and Oliver Langer},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
(R)-[11C]verapamil is a new PET tracer for P-glycoprotein-mediated transport at the blood-brain barrier. For kinetic analysis of (R)-[11C]verapamil PET data the measurement of a metabolite-corrected arterial input function is required. The aim of this study was to assess peripheral (R)-[11C]verapamil metabolism in patients with temporal lobe epilepsy and… CONTINUE READING