Peripheral markers of oxidative stress in chronic mercuric chloride intoxication.

@article{Gutierrez2006PeripheralMO,
  title={Peripheral markers of oxidative stress in chronic mercuric chloride intoxication.},
  author={Lucila Ludmila Paula Gutierrez and Nicolle Gollo Mazzotti and Alex Sander da Rosa Ara{\'u}jo and Rodrigo Klipel and T{\^a}nia G. Fernandes and Susana Francisca Llesuy and Adriane Bell{\'o}-Klein},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2006},
  volume={39 6},
  pages={
          767-72
        }
}
The present study was designed to evaluate the time course changes in peripheral markers of oxidative stress in a chronic HgCl2 intoxication model. Twenty male adult Wistar rats were treated subcutaneously daily for 30 days and divided into two groups of 10 animals each: Hg, which received HgCl2 (0.16 mg kg(-1) day(-1)), and control, receiving the same volume of saline solution. Blood was collected at the first, second and fourth weeks of Hg administration to evaluate lipid peroxidation (LPO… CONTINUE READING
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