Peripheral involvement in nicotine-induced enhancement of ethanol intake.

  title={Peripheral involvement in nicotine-induced enhancement of ethanol intake.},
  author={Mia Ericson and J{\"o}rgen A. Engel and Bo S{\"o}derpalm},
  volume={21 1},
It is a well-known fact that a large percentage of alcoholics smoke, and in the experimental rat, intermittent nicotine administration enhances ethanol intake and ethanol preference in a free-choice situation between 6% (v/v) ethanol and water. The present study focuses on the possible involvement of central and/or peripheral nicotine acetylcholine receptors (nAChR) in nicotine-induced sensitization to dopamine-related behavioral effects of ethanol. Wistar rats drinking less than 60% of their… CONTINUE READING


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