Peripheral dopamine synthesis and metabolism in spontaneously hypertensive rats.

@article{Rcz1985PeripheralDS,
  title={Peripheral dopamine synthesis and metabolism in spontaneously hypertensive rats.},
  author={K{\'a}roly R{\'a}cz and Otto Kuchel and Natalie T. Buu and Sheila Tenneson},
  journal={Circulation research},
  year={1985},
  volume={57 6},
  pages={889-97}
}
We have studied several parameters of peripheral dopamine synthesis and metabolism in spontaneously hypertensive rats during the development of hypertension. Compared to Wistar-Kyoto rats, there was an increased dopamine content in 8-week-old spontaneously hypertensive rats in the adrenals (1.6 +/- 0.1 vs. 1.2 +/- 0.1 nmol/pair in Wistar-Kyoto rats) and kidneys (97 +/- 12 vs. 63 +/- 7 pmol/g tissue in Wistar-Kyoto rats), but the dopamine content in peripheral organs from normotensive 4-week-old… CONTINUE READING
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