Peripheral decrease and pulmonary homing of CD4+CD45RO+ helper memory T cells in cystic fibrosis.

@article{Husler2002PeripheralDA,
  title={Peripheral decrease and pulmonary homing of CD4+CD45RO+ helper memory T cells in cystic fibrosis.},
  author={Martin H{\"a}usler and Klaus Schweizer and S Biesterfel and Thomas Opladen and Gerhard Heimann},
  journal={Respiratory medicine},
  year={2002},
  volume={96 2},
  pages={
          87-94
        }
}
Interstitial lung disease, although of prognostic impact for patients with cystic fibrosis (CF), remains difficult to assess without histopathologic investigations. As changes of peripheral blood lymphocyte subsets (LS) may accompany severe systemic lymphocyte immune responses, we compared peripheral LS of 44 patients with CF, 23 non-CF patients with recurrent pulmonary infections and 83 healthy controls (flow cytometry; CD3, CD19, CD16, CD56, CD4, CD8, CD11b, CD45RA, CD45RO, HLA-DR and CD25… CONTINUE READING