Peripheral blood mononuclear cell interleukin-2 and interferon-gamma production, cytotoxicity, and antigen-stimulated blastogenesis during experimental rhinovirus infection.

@article{Hsia1990PeripheralBM,
  title={Peripheral blood mononuclear cell interleukin-2 and interferon-gamma production, cytotoxicity, and antigen-stimulated blastogenesis during experimental rhinovirus infection.},
  author={Judith A Hsia and Allan L. Goldstein and Gregory L. Simon and Marcelo B. Sztein and Frederick G. Hayden},
  journal={The Journal of infectious diseases},
  year={1990},
  volume={162 3},
  pages={
          591-7
        }
}
To determine whether rhinovirus infection induced a systemic cellular immune response in humans, specific antigen-stimulated blastogenesis, natural killer cell activity, and mitogen-stimulated production of interleukin-2 and interferon-gamma by peripheral blood mononuclear cells (PBMC) were quantified during experimental rhinovirus infection of normal volunteers. Phytohemagglutinin-stimulated interleukin-2 production by PBMC collected on day 5 after rhinovirus inoculation was increased fourfold… CONTINUE READING
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