Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter

@article{MovrareSkrtic2009PeripheralBL,
  title={Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter},
  author={Sofia Mov{\'e}rare-Skrtic and D. D. Mellstr{\"o}m and Liesbeth Vandenput and Mathias Ehrich and C Ohlsson},
  journal={Endocrine},
  year={2009},
  volume={35},
  pages={204-210}
}
Methylation of CpG sites in the promoter region can affect gene transcription. DNA derived from peripheral blood leukocytes (PBL) from the well-characterized clinical cohorts might be useful to study the influence of environmental factors on DNA methylation. However, these studies could be confounded by the heterogeneous nature of PBL. The aims of this… CONTINUE READING