Peripheral blood T cells and monocytes and B cell lines derived from patients with lupus express estrogen receptor transcripts similar to those of normal cells.

@article{Suenaga1998PeripheralBT,
  title={Peripheral blood T cells and monocytes and B cell lines derived from patients with lupus express estrogen receptor transcripts similar to those of normal cells.},
  author={Ronsuke Suenaga and Marilyn J. Evans and Keiji Mitamura and Virginia Rider and Nabih I. Abdou},
  journal={The Journal of rheumatology},
  year={1998},
  volume={25 7},
  pages={1305-12}
}
OBJECTIVE To identify and characterize estrogen receptor (ER) transcripts expressed in immune cells of patients with systemic lupus erythematosus (SLE) and healthy donors. METHODS Peripheral blood monocytes and T cells were prepared from patients with SLE (n = 6) and healthy donors (n = 8). T cells were separated into CD4 and CD8. Some monocytes and T cells were stimulated with estradiol, PMA, and ionomycin. Epstein-Barr virus-transformed B cell lines (n = 7) and B cell hybridomas (n = 2… CONTINUE READING

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