Peripheral biphasic adenocarcinoma of the lung: light microscopic and immunohistochemical findings.


We report two cases of peripheral biphasic adenocarcinoma primary in the lung. To our knowledge, peripheral adenocarcinoma of the lung with a spindle-cell component has not been described previously. Diffuse positive cytokeratin and negative vimentin immunostaining of the spindle-cell components support an epithelial differentiation of the malignant spindle… (More)


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