Peripheral beta‐adrenergic blockade treatment of parkinsonian tremor

@article{Foster1984PeripheralBB,
  title={Peripheral beta‐adrenergic blockade treatment of parkinsonian tremor},
  author={Norman L. Foster and Richard P. Newman and Peter A. Lewitt and Megan McGee Gillespie and T. Andreo Larsen and Thomas Newell Chase},
  journal={Annals of Neurology},
  year={1984},
  volume={16}
}
The effect of nadolol, a peripherally acting beta‐adrenergic blocker, on resting, postural, and intention tremor was examined in 8 patients with idiopathic Parkinson's disease whose motor symptoms, other than tremor, were well controlled with conventional medications. In a double‐blind, placebo‐controlled, crossover design, patients received 80 to 320 mg of nadolol for six weeks while continuing their previous therapeutic regimen. Accelerometer readings showed a 34% reduction (p < 0.025) in… 
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