Peripheral artery disease is associated with a high CD163/TWEAK plasma ratio.

  title={Peripheral artery disease is associated with a high CD163/TWEAK plasma ratio.},
  author={Juan Antonio Moreno and Tiphaine Dejouvencel and J Labreuche and David M Smadja and Micha{\"e}l Dussiot and Jos{\'e}-Luis Martin-Ventura and Jes{\'u}s Egido and Pascale Gaussem and Joseph Emmerich and Jean-Baptiste Michel and Lu{\'i}s Miguel Blanco-Colio and Olivier Meilhac},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={30 6},
OBJECTIVE In addition to its role in the clearance of haptoglobin-hemoglobin (Hp-Hb) complexes, CD163 is a macrophage scavenger receptor for tumor necrosis factor-like weak inducer of apoptosis (TWEAK). We recently reported that the CD163/TWEAK plasma ratio could be a potential biomarker of atherothrombosis in asymptomatic subjects. In this study, we assessed soluble TWEAK (sTWEAK) and soluble CD163 (sCD163) plasma levels in white males with peripheral artery disease (PAD) and in… CONTINUE READING


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