Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls–preliminary findings

@article{Lindqvist2014PeripheralAM,
  title={Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls–preliminary findings},
  author={Daniel Lindqvist and Susanne Mueller and Synthia H Mellon and Yixiong Su and OwenM. Wolkowitz},
  journal={Psychiatry Research: Neuroimaging},
  year={2014},
  volume={224},
  pages={168-174}
}
Several psychiatric disorders, including major depressive disorder (MDD), are associated with increased blood markers of oxidative stress. The relevance of this to the oxidation-sensitive hippocampus (HC) is unknown. We investigated the relationship between peripheral oxidative stress markers and HC volume in unmedicated individuals with MDD (n=16) and healthy controls (n=19). To conserve power, our primary analysis was carried out in the combined group of subjects, and secondary analyses… CONTINUE READING
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