Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats.

@article{Schreiber2012PeripheralAE,
  title={Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats.},
  author={Anne Karoline Schreiber and Manuele Neufeld and Carlos Henrique Alves Jesus and Joice Maria da Cunha},
  journal={Neuropharmacology},
  year={2012},
  volume={63 8},
  pages={1286-97}
}
Diabetes is often associated with painful neuropathy. The current treatments are symptomatic and ineffective. Cannabinoids have been proposed as promising drugs for chronic pain treatment and its antinociceptive effect has already been related in nerve injury models of neuropathic pain, but little has been investigated in painful diabetic neuropathy models. Thus, the current study aims to investigate the potential antinociceptive effect of drugs that alter endocannabinoid system when injected… CONTINUE READING
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