Peripheral B cell subsets.


Our understanding of the origins and the biological functions of different peripheral B cell subsets continues to evolve. Some understanding has been obtained regarding the synergy between BCR-derived signals and other receptors and signaling pathways that drive the development of follicular, marginal zone, and B-1 B cells, but this remains a complex and poorly understood issue. More recent information regarding the origins of B-1 and B-2 B cells, the ability of follicular B cells to mature both in the bone marrow and the spleen, the existence of a definable precursor for MZ B cells, and the ability of follicular B cells to occupy two distinct niches are all highlighted in this review.

DOI: 10.1016/j.coi.2008.03.014
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@article{Allman2008PeripheralBC, title={Peripheral B cell subsets.}, author={David M. Allman and Shiv S Pillai}, journal={Current opinion in immunology}, year={2008}, volume={20 2}, pages={149-57} }