Periparturient dairy cows do not exhibit hepatic insulin resistance, yet adipose-specific insulin resistance occurs in cows prone to high weight loss.

@article{Zachut2013PeriparturientDC,
  title={Periparturient dairy cows do not exhibit hepatic insulin resistance, yet adipose-specific insulin resistance occurs in cows prone to high weight loss.},
  author={Maya Zachut and H. Job Honig and S. Striem and Yehiel Zick and Sigalit Boura-Halfon and Uzi Moallem},
  journal={Journal of dairy science},
  year={2013},
  volume={96 9},
  pages={5656-69}
}
The periparturient period in dairy cows is associated with alterations in insulin action in peripheral tissues; however, the molecular mechanism underlying this process is not completely understood. The objective was to examine the response to a glucose tolerance test (GTT) and to analyze insulin signaling in liver and adipose tissues in pre- and postpartum dairy cows. Liver and adipose tissue biopsies were taken before and after GTT, at 17d prepartum and again at 3 to 5d postpartum from 8 high… CONTINUE READING