Peripartum cardiomyopathy: a comprehensive review.

@article{Abboud2007PeripartumCA,
  title={Peripartum cardiomyopathy: a comprehensive review.},
  author={John Abboud and Yahya Murad and Carol A Chen-Scarabelli and Louis I.I. Saravolatz and Tiziano M. Scarabelli},
  journal={International journal of cardiology},
  year={2007},
  volume={118 3},
  pages={
          295-303
        }
}
Peripartum cardiomyopathy (PPCM) is a rare disorder in which left ventricular dysfunction and symptoms of heart failure occur in the peripartum period in previously healthy women. Incidence of PPCM ranges from 1 in 1300 to 1 in 15,000 pregnancies. The etiology of PPCM is unknown, but viral, autoimmune, and idiopathic causes may contribute. The diagnostic criteria are onset of heart failure in the last month of pregnancy or in first 5 months postpartum, absence of determinable cause for cardiac… Expand
Peripartum Cardiomyopathy: A Systematic Review
TLDR
Because of its rare incidence, geographical differences, and heterogeneous presentation, PPCM continues to be incompletely characterized and understood, so future epidemiological trials and national registries are needed to learn more about the disease. Expand
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Peripartum cardiomyopathy, a type of dilated cardiomyopathy of unknown origin, occurs in previously healthy women in the final month of pregnancy and up to 5 months after delivery. Although theExpand
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  • 2013
TLDR
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TLDR
Health professionals are made aware of the possibilities in a woman with dyspnoea in the postpartum period as early diagnosis and medical treatment may affect the patient’s long-term prognosis. Expand
Can peripartum cardiomyopathy be familial?
TLDR
The observation emphasizes the interest of cardiac magnetic resonance imaging in the investigation of an acute heart failure occurring during the peripartum and allows us to evoke a genetic predisposition in some cases of PPCM, to discuss the fact that some forms of familial PPCm could be unknown familial dilated cardiomyopathy unmasked by pregnancy, and to wonder on the familial screening modalities. Expand
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TLDR
An overview on the clinical appearance and management, risk factors and potential pathophysiological mechanisms of PPCM, and pharmacological blockade of prolactin holds the promise of novel, more disease-specific therapy options. Expand
An update on treatments and outcomes in peripartum cardiomyopathy.
TLDR
Therapies for chronic heart failure from PPCM are similar to those patients with nonischemic cardiomyopathy from different etiologies, however novel therapies may include bromocriptine, pentoxifylline or other potential therapies influencing the immune system. Expand
Peripartum cardiomyopathy in Africa: challenges in diagnosis, prognosis, and therapy.
TLDR
Recent prospective long-term follow-up of patients with PPCM in developing societies suggest recovery occurring only well into the second year after diagnosis, and recovery is poorly predicted by baseline left ventricular function. Expand
Peripartum Cardiomyopathy-A Case Report
Peripartum cardiomyopathy (PPCM) is a dilated cardiomyopathy defined as systolic cardiac heart failure in the last month of pregnancy or within five months of delivery. Its diagnosis is often delayedExpand
Peripartum Cardiomyopathy Reached Progressive Recovery Despites Poor Initial Ejection Fraction
TLDR
A rare case which was first misdiagnosed but had a continuous progressive recovery of LV systolic function (LVSF) within five years after it was finally diagnosed and treated is presented. Expand
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References

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Peripartum cardiomyopathy: a review of the literature.
TLDR
The reader will be able to understanding the typical presentation of peripartum cardiomyopathy including adverse outcome predictors, to understand how to make the diagnosis of PPCM and how to manage it, and to understand the natural history of the disease. Expand
Peripartum cardiomyopathy: an ominous diagnosis.
TLDR
The unique hemodynamic stresses of pregnancy unmask previously undiagnosed cardiomyopathy in otherwise medically stable individuals and the prognosis for these patients is guarded. Expand
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TLDR
The case of a 38 years old woman, who developed in an 33rd week of gestation a PPCM, who had some risk factors (include preeclampsia) but had a favorable evolution with conventional treatment, is presented. Expand
Incidence of myocarditis in peripartum cardiomyopathy.
TLDR
A retrospective review of endomyocardial biopsy specimens from 34 patients fulfilling the criteria for a diagnosis of PC showed a lower incidence of myocarditis than that reported in other studies, and factors that may influence the diverse range in the reported incidence are discussed. Expand
Peripartum cardiomyopathy: Clinical, hemodynamic, histologic and prognostic characteristics
TLDR
In an effort to characterize this syndrome in a middle class population, 14 consecutive patients with peripartum cardiomyopathy underwent a detailed history and physical examination, right heart catheterization, M-mode and two-dimensional echocardiography, radionuclide ventriculography and right ventricular endomyocardial biopsy, to determine prognostic indicators. Expand
Is peripartum cardiomyopathy an organ-specific autoimmune disease?
TLDR
A more thorough study of the precise nature of the cardiac tissue autoantigens may lead to the identification of the mechanisms of breakdown of self-tolerance and perhaps also the putative etiologic agent(s). Expand
Peripartum cardiomyopathy. A role for cardiac stress determinants other than pregnancy?
TLDR
A review of previously published cases reveals the frequent association of multiple nonspecific cardiac stress factors that may predispose women to peripartum cardiomyopathy. Expand
Natural Course of Peripartum Cardiomyopathy
TLDR
In those patients in whom cardiomegaly persisted, the prognosis was poor, and subsequent pregnancies were likely to lead to permanent deterioration, but in those in whom the heart size returned to normal the prog outlook was excellent. Expand
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TLDR
The available literature on peripartum cardiomyopathy, with particular attention to reported cases, is reviewed to define this condition as a definite syndrome and to predict the most frequent mode of presentation, the course of the disease, and the pathologic findings that are often reported with this entity. Expand
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TLDR
The authors conclude that idiopathic peripartum cardiomyopathy is uncommon, and that in most women with periparum heart failure of obscure etiology, underlying chronic disease will be identified. Expand
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