Peripartum cardiomyopathy: Current therapeutic perspectives

@article{Phillips2004PeripartumCC,
  title={Peripartum cardiomyopathy: Current therapeutic perspectives},
  author={S. Phillips and C. Warnes},
  journal={Current Treatment Options in Cardiovascular Medicine},
  year={2004},
  volume={6},
  pages={481-488}
}
Peripartum cardiomyopathy is a rare condition of unclear etiology that accounts for an important percentage of pregnancy-related deaths. Deaths from peripartum cardiomyopathy can be attributed to profound left ventricular failure, thromboembolic events, or arrhythmia. Prompt recognition of the condition, initiation of appropriate medical management, collaboration with perinatology for delivery management, referral to cardiac transplant centers when necessary, and counseling regarding future… Expand
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TLDR
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TLDR
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TLDR
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TLDR
In patients with PPCM, long-term survival is better than has been historically reported, the prevalence of myocarditis is high, and decreased left ventricular stroke work index is associated with worse clinical outcomes. Expand
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TLDR
In patients with peripartum cardiomyopathy, the etiology remains unclear although myocarditis was present in 78% of those with this condition, and resolution of mycarditis is associated with significant improvement in left ventricular function. Expand
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In those patients in whom cardiomegaly persisted, the prognosis was poor, and subsequent pregnancies were likely to lead to permanent deterioration, but in those in whom the heart size returned to normal the prog outlook was excellent. Expand
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TLDR
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TLDR
Peripartum cardiomyopathy is a rare lethal disease about which little is known and diagnosis is confined to a narrow period and requires echocardiographic evidence of left ventricular systolic dysfunction. Expand
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TLDR
Subsequent pregnancy in women with a history of peripartum cardiomyopathy is associated with a significant decrease in left ventricular function and can result in clinical deterioration and even death. Expand
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