Peripapillary retinal nerve fibre layer thickness in individuals with epilepsy exposed to vigabatrin

@inproceedings{Clayton2011PeripapillaryRN,
  title={Peripapillary retinal nerve fibre layer thickness in individuals with epilepsy exposed to vigabatrin},
  author={Lisa M. S. Clayton},
  year={2011}
}
Background: The antiepileptic drug vigabatrin (VGB) is associated with the development of visual field loss in around 50% of exposed individuals. The mechanisms of VGB retinotoxicity are unknown, and there is continued debate as to the best methods of assessing visual function in VGB-exposed individuals, particularly in those unable to perform perimetry. Methods: 204 VGB-exposed individuals, 90 non-exposed individuals with epilepsy and 90 healthy controls participated. Individuals underwent… CONTINUE READING

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