Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice.

@article{Ros2008PeriostinIE,
  title={Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice.},
  author={H{\'e}ctor Felipe Cardona R{\'i}os and Dik-Lung Ma and Yu-feng Xie and William V Giannobile and Lynda F Bonewald and Simon James Conway and Jin Qiao Feng},
  journal={Journal of periodontology},
  year={2008},
  volume={79 8},
  pages={
          1480-90
        }
}
BACKGROUND The ability of the periodontal ligament (PDL) to absorb and distribute forces is necessary for periodontal homeostasis. This adaptive response may be determined, in part, by a key molecule, periostin, which maintains the integrity of the PDL during occlusal function and inflammation. Periostin is primarily expressed in the PDL and is highly homologous to betaig-H3 (transforming growth factor-beta [TGF-beta] inducible gene). Cementum, alveolar bone, and the PDL of periostin-null mice… CONTINUE READING

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