Perioperative complications with rhBMP-2 in transforaminal lumbar interbody fusion

  title={Perioperative complications with rhBMP-2 in transforaminal lumbar interbody fusion},
  author={Kirk Owens and Steven Glassman and Jennifer M. Howard and Mladen O Djurasovic and Jonathan L. Witten and Leah Yacat Carreon},
  journal={European Spine Journal},
Bone morphogenetic protein (BMP) is commonly used as an ICBG substitute for transforaminal lumbar interbody spine fusion (TLIF). However, multiple recent reports have raised concerns regarding a substantial incidence of perioperative radiculopathy. Also, given the serious complications reported with anterior cervical BMP use, risks related to swelling and edema with TLIF need to be clarified. As TLIF related complications with rhBMP-2 have generally been reported in small series or isolated… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 30 extracted citations


Publications referenced by this paper.
Showing 1-10 of 37 references

a report of five cases

  • KU Lewandrowski, C Nanson, 2 Calderon R Vertebral osteolysis after posterior in protein
  • Spine J 7:609–614 Eur Spine J
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…