Perioperative blood transfusions are associated with increased rates of recurrence and decreased survival in patients with high-grade soft-tissue sarcomas of the extremities.

@article{Rosenberg1985PerioperativeBT,
  title={Perioperative blood transfusions are associated with increased rates of recurrence and decreased survival in patients with high-grade soft-tissue sarcomas of the extremities.},
  author={Saul A. Rosenberg and Claudia A. Seipp and Donald E. White and Robert C. Wesley},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1985},
  volume={3 5},
  pages={698-709}
}
One hundred fifty-six patients with high-grade soft-tissue sarcomas of the extremities treated on prospective randomized trials were analyzed to determine the impact of perioperative blood transfusions on tumor recurrence and patient survival. A significant increase in the incidence of tumor recurrence and decrease in survival were associated with the receipt of blood transfusions at the time of definitive surgical therapy of the sarcoma. Actuarial 5-year continuous disease-free survival was 70… CONTINUE READING

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