Perioperative Dexamethasone and the Development of Chronic Postmastectomy Pain: A Single-Center Observational Cohort Study

@article{deOliveira2015PerioperativeDA,
  title={Perioperative Dexamethasone and the Development of Chronic Postmastectomy Pain: A Single-Center Observational Cohort Study},
  author={Gild{\`a}sio S. de Oliveira and Jane M Bialek and Alparslan Turan and Robert J. McCarthy and Daniel I. Sessler},
  journal={Regional Anesthesia \& Pain Medicine},
  year={2015},
  volume={40},
  pages={539 - 544}
}
Background and Objectives Perioperative modulation of the surgical inflammatory response has been hypothesized as a viable pharmacological preventive target for the development of chronic pain after surgery. The objective of the current investigation was to evaluate an association between intravenous dexamethasone 4 to 20 mg on the day of surgery with self-reported pain in the breast or axilla 3 months or more after mastectomy. Methods The study was a secondary data analysis of a prospective… 
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Prevalence of pain in patients with breast cancer post-treatment: A systematic review.
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Data is presented from recently published studies examining the incidence, risk factors, mechanisms, treatment options, and preventive strategies for chronic postoperative pain in adults to highlight the importance of the trajectory of acute pain and the fact that catastrophizing may not always be predictive.
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This quantitative analysis of randomized controlled trials demonstrates that the Pecs block is effective for reducing postoperative opioid consumption and pain in patients undergoing mastectomy.
C-reactive Protein Level on Postoperative Day One is Associated with Chronic Postsurgical Pain After Mastectomy
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Postoperative CRP level is likely to be associated with the development of CPSP after mastectomy, and pain intensity of APSP and CRP levels on postoperative day one was significantly associated with anesthetic managements.
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Clinical investigations evaluating different preventative pharmacologic strategies that are routinely used by anesthesiologists in their daily clinical practices for preventing persistent postoperative pain are described.
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Clinical investigations evaluating different preventative pharmacologic strategies that are routinely used by anesthesiologists in their daily clinical practices for preventing persistent postoperative pain are described.
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It has been recommended that more than one analgesic modality (multimodal analgesia) will be necessary to achieve adequate perioperative pain control, thus avoiding the unwanted effects of large doses of single analgesics, in particular opioids.
Unexplained pain after scheduled limb surgery.
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