Periodontitis in systemic rheumatic diseases

@article{Pablo2009PeriodontitisIS,
  title={Periodontitis in systemic rheumatic diseases},
  author={Paola de Pablo and Iain Chapple and Christopher D. Buckley and Thomas Dietrich},
  journal={Nature Reviews Rheumatology},
  year={2009},
  volume={5},
  pages={218-224}
}
Periodontitis is a chronic inflammatory disease that is characterized by loss of the periodontal ligament and alveolar bone, and is a major cause of tooth loss. Results from clinical and epidemiologic studies have suggested that periodontitis and tooth loss are more prevalent in individuals with rheumatoid arthritis (RA). However, the strength and temporality of the association are uncertain. Several biologically plausible causal and noncausal mechanisms might account for this association… 
Rheumatoid arthritis and periodontal disease : biological , clinical , and therapeutic relations
A number of clinical and epidemiological studies have been conducted in the past decade to investigate a possible association between periodontal disease and rheumatoid arthritis (RA). The majority
Link between rheumatoid arthritis and chronic periodontitis
TLDR
The current knowledge about the link between both diseases is reviewed, focusing on its clinical implications and will periodontal treatment become a part of standard therapy for rheumatoid arthritis.
Studies on the relationship between periodontitis and rheumatoid arthritis
TLDR
The severity of periodontitis in relation to ACPA/RF status, immunological parameters associated with RA, and the presence of subgingival P. gingivalis DNA in patients with established RA was investigated.
Potential mechanisms linking periodontitis to rheumatoid arthritis.
TLDR
The search for the possible mechanism linking PD to RA continues as it can play an important role in enabling early intervention in the form of prevention and treatment of infection and reduce societal burden related to increased patient discomfort and treatment costs.
Editorial: Marginal Jawbone Loss Is Associated With the Onset of Rheumatoid Arthritis and Is Related to the Plasma Level of RANKL
TLDR
The association betweenperiodontitis and RA may be very important from both a clinical and a public health perspective, because there are several processes through which chronic periodontitis may be part of a causal pathway in the pathogenesis of RA.
Rheumatoid Arthritis and Periodontitis-Plausible Inflammatory Link
TLDR
Data suggest that periodontal therapies combined with routine RA treatments further improve RA status, and enlightens the link between periodontitis and rheumatoid arthritis.
Association of periodontitis with rheumatoid arthritis and atherosclerosis: Novel paradigms in etiopathogeneses and management?
  • M. Soory
  • Medicine
    Open access rheumatology : research and reviews
  • 2010
TLDR
Existing data supports the hypothesis that persistent localized infection in periodontitis may influence systemic levels of inflammatory markers and pose a risk for RA and atherosclerosis.
Chronic Inflammation ; Periodontitis with rheumatoid Arthritis & atherosclerosis : When-Where-How ?
There is increasing documentation of a link between inflammatory periodontal disease affecting the supporting structure of teeth, rheumatoid arthritis, and coronary artery disease. Periodontitis is
Is Periodontitis and Rheumatoid Arthritis Inter-Related?
TLDR
It seems that a decrease in periodontal inflammation in some way influences the level of systemic inflammation, and appears to contribute to the clinical improvement of the disease.
Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions
TLDR
An overview of the relationship between rheumatoid arthritis and periodontal disease is provided, exploring the similarities in the immune-pathological aspects and the possible mechanisms linking the development and progression of both diseases.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 160 REFERENCES
Periodontal diseases and osteoporosis: association and mechanisms.
TLDR
The majority of studies have shown low bone mass to be independently associated with loss of alveolar crestal height and tooth loss, however studies that focus on the relation of clinical attachment loss and osteoporosis are less consistent.
Association among rheumatoid arthritis, oral hygiene, and periodontitis.
TLDR
Subjects with RA have significantly increased periodontal attachment loss compared to controls, and poor oral hygiene may only partially account for this association.
Periodontal and hematological characteristics associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis.
TLDR
Both differences and similarities in periodontal and hematological variables were seen in individuals with periodontitis, JIA, and RA.
Relationship between rheumatoid arthritis and periodontitis.
TLDR
When the percentage of bone loss was compared with various indicators of rheumatoid arthritis disease activity, it was found that swollen joints, health assessment questionnaire scores, levels of C-reactive protein, and erythrocyte sedimentation rate were the principal parameters which could be associated with periodontal bone loss.
Risk for periodontal disease in patients with longstanding rheumatoid arthritis.
TLDR
Patients with longstanding active RA have a substantially increased frequency of periodontal disease, including loss of teeth, compared with controls, and antiinflammatory treatment interferes with periodontals disease and might have masked a possible correlation between the indices of chronic destruction.
Periodontal condition in patients with rheumatoid arthritis.
TLDR
There is an association between periodontal disease and rheumatoid arthritis, and it is suggested that the prevalence of dental plaque was higher in the test group than in the control group.
Gingivitis and periodontitis are related to repeated high levels of circulating tumor necrosis factor-alpha in patients with rheumatoid arthritis.
TLDR
Gingivitis and periodontitis are related to high levels of circulating TNF-alpha in patients with rheumatoid arthritis.
Association of periodontal disease and tooth loss with rheumatoid arthritis in the US population.
TLDR
RA may be associated with tooth loss and periodontitis and in participants with seropositive RA there was a stronger association with dental health status, in particular with edentulism.
Periodontal conditions in adults with rheumatoid arthritis.
TLDR
The RA-patients had less plaque and calculus than the control group, a finding which could indicate a difference in periodontal care.
Changes in periodontal and rheumatological conditions after 2 years in patients with juvenile idiopathic arthritis.
TLDR
The erythrocyte sedimentation rate and clinical rheumatological parameters were significantly improved at the 2-year follow-up, and no clinical or laboratory differences could be found between JIA patients and control subjects.
...
1
2
3
4
5
...