Periodontitis and Systemic Inflammation: Control of the Local Infection is Associated with a Reduction in Serum Inflammatory Markers

  title={Periodontitis and Systemic Inflammation: Control of the Local Infection is Associated with a Reduction in Serum Inflammatory Markers},
  author={Francesco D’Aiuto and Mohamed H. Parkar and Georgios Andreou and Jean Suvan and Peter M. Brett and Derren R Ready and Maurizio S. Tonetti},
  journal={Journal of Dental Research},
  pages={156 - 160}
Severe periodontitis is associated with elevated inflammatory markers in otherwise healthy populations. However, the nature of this association has not been determined. Our aim was to assess whether the degree of response to periodontal therapy was associated with changes in serological markers of systemic inflammation. Ninety-four systemically healthy subjects with severe generalized periodontitis participated in a prospective six-month blind intervention trial. Periodontal parameters and… 

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