Periodontal treatment decreases levels of antibodies to Porphyromonas gingivalis and citrulline in patients with rheumatoid arthritis and periodontitis.

@article{Okada2013PeriodontalTD,
  title={Periodontal treatment decreases levels of antibodies to Porphyromonas gingivalis and citrulline in patients with rheumatoid arthritis and periodontitis.},
  author={Moe Okada and Tetsuo Kobayashi and Satoshi Ito and Tomoko Yokoyama and Asami Abe and Akira Murasawa and Hiromasa Yoshie},
  journal={Journal of periodontology},
  year={2013},
  volume={84 12},
  pages={e74-84}
}
BACKGROUND Porphyromonas gingivalis has been implicated as an etiologic agent of rheumatoid arthritis (RA) because of the expression of peptidylarginine deiminase. The present study evaluates whether periodontal treatment may affect serum antibodies to P. gingivalis and citrulline levels in relation to disease activity of RA. METHODS Fifty-five patients with RA were randomly assigned to receive oral hygiene instruction and supragingival scaling (treatment group, n = 26) or no periodontal… CONTINUE READING
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