Periodontal regeneration in human Class II furcations using purified recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with bone allograft.

@article{Camelo2003PeriodontalRI,
  title={Periodontal regeneration in human Class II furcations using purified recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with bone allograft.},
  author={Marcelo Camelo and Marc L Nevins and Robert K. Schenk and Samuel Lynch and Myron Nevins},
  journal={The International journal of periodontics & restorative dentistry},
  year={2003},
  volume={23 3},
  pages={213-25}
}
This human clinical trial evaluated the clinical and histologic response to recombinant human platelet-derived growth factor-BB (rhPDGF-BB) delivered in bone allograft for the treatment of advanced Class II furcation defects. Three mandibular and one maxillary molar furcation defects were treated: Two received 0.5 mg/mL and two received 1.0 mg/mL rhPDGF-BB, in all cases mixed with DFDBA. Clinical probing depths and attachment levels were obtained presurgically and 9 months postsurgical, after… CONTINUE READING